- Corporate Officers - G
- George Simeon
Insider Trading History of George Simeon
The following table details the insider trading activities
(stock purchases, stock sales, and stock option exercises) of George Simeon since 2016.
This trader's CIK number is 1595117.
At the time of last reporting, George Simeon was the Officer of Avalyn Pharma Inc.. (stock ticker symbol AVLN).
Also see all insider trading activities at Avalyn Pharma Inc..
Note that in the past
George Simeon also reported insider trading activities as an insider of the following companies:
Yearly summary of insider trading at Design Therapeutics, Inc. (DSGN) by George Simeon
| | Insider Buying | Insider Sales | Option Exercises |
|---|
| Year | Symbol | Shares | Value | Shares | Value | Shares | Value |
|---|
| 2022 | DSGN | 900,000 | $7,574,179 | 0 | $0 | 0 | $0 |
| 2021 | DSGN | 250,000 | $5,000,000 | 0 | $0 | 0 | $0 |
Yearly summary of insider trading at Turning Point Therapeutics, Inc. (TPTX) by George Simeon
| | Insider Buying | Insider Sales | Option Exercises |
|---|
| Year | Symbol | Shares | Value | Shares | Value | Shares | Value |
|---|
| 2020 | TPTX | 83,333 | $4,999,980 | 0 | $0 | 0 | $0 |
| 2019 | TPTX | 502,777 | $13,849,965 | 0 | $0 | 0 | $0 |
Yearly summary of insider trading at Nkarta, Inc. (NKTX) by George Simeon
| | Insider Buying | Insider Sales | Option Exercises |
|---|
| Year | Symbol | Shares | Value | Shares | Value | Shares | Value |
|---|
| 2022 | NKTX | 1,333,333 | $19,999,995 | 0 | $0 | 0 | $0 |
Yearly summary of insider trading at Effector Therapeutics, Inc. (EFTR) by George Simeon
| | Insider Buying | Insider Sales | Option Exercises |
|---|
| Year | Symbol | Shares | Value | Shares | Value | Shares | Value |
|---|
| 2023 | EFTR | 0 | $0 | 609,163 | $369,761 | 0 | $0 |
Yearly summary of insider trading at Avalyn Pharma Inc. (AVLN) by George Simeon
| | Insider Buying | Insider Sales | Option Exercises |
|---|
| Year | Symbol | Shares | Value | Shares | Value | Shares | Value |
|---|
| 2026 | AVLN | 555,555 | $9,999,990 | 0 | $0 | 0 | $0 |
Yearly summary of insider trading at Principia Biopharma Inc. (PRNB) by George Simeon
| | Insider Buying | Insider Sales | Option Exercises |
|---|
| Year | Symbol | Shares | Value | Shares | Value | Shares | Value |
|---|
| 2019 | PRNB | 357,142 | $9,999,976 | 0 | $0 | 0 | $0 |
| 2018 | PRNB | 270,000 | $4,590,000 | 0 | $0 | 0 | $0 |
Yearly summary of insider trading at Zenas Biopharma, Inc. (ZBIO) by George Simeon
| | Insider Buying | Insider Sales | Option Exercises |
|---|
| Year | Symbol | Shares | Value | Shares | Value | Shares | Value |
|---|
| 2025 | ZBIO | 126,315 | $2,399,985 | 0 | $0 | 0 | $0 |
| 2024 | ZBIO | 2,235,294 | $37,999,998 | 0 | $0 | 0 | $0 |
Yearly summary of insider trading at Crispr Therapeutics Ag (CRSP) by George Simeon
| | Insider Buying | Insider Sales | Option Exercises |
|---|
| Year | Symbol | Shares | Value | Shares | Value | Shares | Value |
|---|
| 2025 | CRSP | 2,969,436 | $154,499,754 | 0 | $0 | 0 | $0 |
| 2016 | CRSP | 66,500 | $931,000 | 0 | $0 | 0 | $0 |
Insider trading activities at 8 companies by George Simeon:
1. Design Therapeutics, Inc. (DSGN)
2. Turning Point Therapeutics, Inc. (TPTX)
3. Nkarta, Inc. (NKTX)
4. Effector Therapeutics, Inc. (EFTR)
5. Avalyn Pharma Inc. (AVLN)
6. Principia Biopharma Inc. (PRNB)
7. Zenas Biopharma, Inc. (ZBIO)
8. Crispr Therapeutics Ag (CRSP)
Table 1. Insider trading of Design Therapeutics, Inc. (DSGN) by George Simeon
| Trade Date | Symbol | Trade Type | Shares | Price ($) | Value ($) |
|---|
| 2022-12-16 | DSGN | Buy | 500,000 | 8.28 | 4,140,500 |
| 2022-12-19 | DSGN | Buy | 360,000 | 8.63 | 3,108,240 |
| 2022-12-20 | DSGN | Buy | 40,000 | 8.14 | 325,439 |
| 2021-03-30 | DSGN | Buy | 250,000 | 20.00 | 5,000,000 |
Table 2. Insider trading of Turning Point Therapeutics, Inc. (TPTX) by George Simeon
| Trade Date | Symbol | Trade Type | Shares | Price ($) | Value ($) |
|---|
| 2020-05-21 | TPTX | Buy | 83,333 | 60.00 | 4,999,980 |
| 2019-09-10 | TPTX | Buy | 177,777 | 45.00 | 7,999,965 |
| 2019-04-22 | TPTX | Buy | 325,000 | 18.00 | 5,850,000 |
Table 3. Insider trading of Nkarta, Inc. (NKTX) by George Simeon
| Trade Date | Symbol | Trade Type | Shares | Price ($) | Value ($) |
|---|
| 2022-04-28 | NKTX | Buy | 1,333,333 | 15.00 | 19,999,995 |
Table 4. Insider trading of Effector Therapeutics, Inc. (EFTR) by George Simeon
| Trade Date | Symbol | Trade Type | Shares | Price ($) | Value ($) |
|---|
| 2023-11-27 | EFTR | Sale | 609,163 | .61 | 369,761 |
Table 5. Insider trading of Avalyn Pharma Inc. (AVLN) by George Simeon
| Trade Date | Symbol | Trade Type | Shares | Price ($) | Value ($) |
|---|
| 2026-05-01 | AVLN | Buy | 555,555 | 18.00 | 9,999,990 |
Table 6. Insider trading of Principia Biopharma Inc. (PRNB) by George Simeon
| Trade Date | Symbol | Trade Type | Shares | Price ($) | Value ($) |
|---|
| 2019-10-18 | PRNB | Buy | 357,142 | 28.00 | 9,999,976 |
| 2018-09-18 | PRNB | Buy | 270,000 | 17.00 | 4,590,000 |
Table 7. Insider trading of Zenas Biopharma, Inc. (ZBIO) by George Simeon
| Trade Date | Symbol | Trade Type | Shares | Price ($) | Value ($) |
|---|
| 2025-10-09 | ZBIO | Buy | 126,315 | 19.00 | 2,399,985 |
| 2024-09-16 | ZBIO | Buy | 2,235,294 | 17.00 | 37,999,998 |
Table 8. Insider trading of Crispr Therapeutics Ag (CRSP) by George Simeon
| Trade Date | Symbol | Trade Type | Shares | Price ($) | Value ($) |
|---|
| 2025-07-16 | CRSP | Buy | 989,812 | 52.03 | 51,499,918 |
| 2025-07-16 | CRSP | Buy | 989,812 | 52.03 | 51,499,918 |
| 2025-07-16 | CRSP | Buy | 989,812 | 52.03 | 51,499,918 |
| 2016-10-24 | CRSP | Buy | 66,500 | 14.00 | 931,000 |
Insider trading activities including stock purchases, stock sales, and option exercises
listed in the above table cannot be completely guaranteed as to their accuracy.
For more information regarding the trades made by George Simeon
(Officer of Avalyn Pharma Inc. at the time of this reporting) see
the Securities and Exchange Commission (SEC) website.